ESLD

End stage liver disease (ESLD), also known as the final stage liver failure, is an irreversible liver condition that occurs due to acute liver failure or chronic liver diseases resulting in disruption of hepatic parenchyma (liver cells) and the adjacent structures...

New Potential Biomarker for MASH

This 30 July 2025 Gut article “Thrombospondin‑2 is a performant biomarker of at‑risk MASH and advanced MASH fibrosis in a large multicentre European cohort” is revealing; a snapshot of the future. 🧠 Background & Objective Clinical need exists for non‑invasive,...

ED HCV Screening

Here’s a summary of the ContagionLive article “Non‑Targeted Hepatitis C Screening in Emergency Departments Increases Diagnoses” (published July 21, 2025): 🧬 Findings from the DETECT Hep C Trial 1. Study Design & Rationale The DETECT Hep C trial was a large...

PFIC Explained

Progressive familial intrahepatic cholestasis (PFIC) is a rare genetic disorder that causes severe itchiness and liver failure. Patients with PFIC develop liver failure as a result of a buildup of a digestive fluid known as bile. PFIC is a group of rare genetic...

FIB-4 Index

At the core of diagnosing — and surveilling longitudinal care — is the FIB-4, from a standard CBC aka Complete Blood Count (bloodwork), from a venipuncture e.g., at Quest or Labcorp.This is irrespective of fast-rising Transient Liver Elastography, a...