Liver needs one of these: HHS Announces $4 Million KidneyX EMPOWER Prize Challenge and Health Technology Project to Advance Living Kidney Donation and Patient-Centered Innovation.
Key quote:
The $4 million EMPOWER Prize Challenge directly targets these challenges by seeking bold, practical solutions that improve (see below) ….

The Takeaway
HHS launched the 2026 KidneyX EMPOWER Prize Challenge, a $4 million national competition to drive innovation that increases living kidney donation and improves support for donors and patients.
The Why
- Nearly 100,000 Americans are waiting for a kidney transplant, and over a dozen die daily while waiting.
- Living kidney donation is highly effective but has stagnated (<7,000 donors/year) for ~20 years.
- Barriers include financial, logistical, educational, and social challenges that deter donors.
The competition (run by KidneyX) seeks practical, scalable solutions to remove barriers and expand access to living donation.
Focus Areas (5 Pillars)
- Public awareness & mentorship – identify and support potential donors
- Donor interventions – address fears about surgery and long-term health
- Donor readiness & eligibility – help with issues like BMI, smoking, finances
- Donor-centered outcomes – improve long-term monitoring and support
- Center practices – reduce administrative delays and share best practices
Essential Nuance
Alongside the prize, HHS is working on health data standardization and interoperability in kidney care to improve:
- care coordination
- clinical decision-making
- research and innovation
Bottom Line
HHS is using a prize-based innovation model to tackle the persistent shortage of living kidney donors—pairing patient-centered solutions + better data infrastructure to increase transplants and improve outcomes nationwide.